Institute of Chemical Technology, Mumbai

Prof. Prashant S. Kharkar

Professor

Department : Pharmaceutical Sciences and Technology

Date of Joining :19/10/2019

URL : https://prashantkharkar.in/

Email Address : ps.kharkar[@]ictmumbai.edu.in

Phone [Mobile] 9819467123

Office Extention : 2225

Research Area : Design, Synthesis, Biological Evaluation and Preclinical Development of New Chemical Entities (NCEs) as Therapeutic Agents; Study of Biofilm-Forming and Quorum-Sensing Inhibitors in Gram-Negative Bacterial Pathogens; Discovery of Potential Antitubercular Agents Targeting MtbGuaB2; Discovery of Novel Cancer Stem Cell (CSC) Inhibitors; Computational Prediction of Toxicity Properties of Small Molecules; Development of Novel Fluorescent Probes for Biomedical Applications

Academic Information
Degree/Diploma Description year subject
1 Post Doc   Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI, USA (2006-2009) 2009 Medicinal Chemistry
2 Ph.D.   Institute of Chemical Technology (ICT), Mumbai 2004 Pharmaceutical Chemistry
3 M. Pharm. Sci.   Institute of Chemical Technology (ICT), Mumbai 2000 Pharmaceutical Chemistry
4 B. Pharm   N. D. M. V. P. S.'s College of Pharmacy, Nasik 1998 Pharmacy

Courses Taught : Undergraduate: Pharmaceutical Organic Chemistry I; Pharmaceutical Organic Chemistry II; Pharmaceutical Organic Chemistry III; Medicinal Chemistry I; Medicinal Chemistry II; Medicinal Chemistry III; Pharmaceutical Analysis I; Pharmaceutical Analytical Approaches III; Drug Regulatory Affairs; Business Analytics Postgraduate: Modern Pharmaceutical Analytical Approaches; Biopharmaceutics and Pharmacokinetics; Computer Aided Drug Development; Pharmaceutical Validation; Advanced Pharmaceutical Chemistry; Pharmaceutical Analysis and Green Chemistry

Project Information
1 Consultancy Project Handled Ongoing: ‘Mechanistic Understanding on Volatiles and Sorbents Interaction using Computational Tools’ sponsored by Unilever Industries Pvt. Ltd., Bangalore (May 2023 - August 2023)    MAY  2023      
2 Consultancy Project Handled Ongoing: ‘Multiscale Modeling and MD Simulations – Mechanistic Understanding on Volatiles and Sorbent Interaction’ sponsored by Unilever Industries Pvt. Ltd., Bangalore (May 2023-March 2024)    MAY  2023      
3 Consultancy Project Handled Ongoing: 'Development of Novel Anticancer Agents and Cancer Stemness Inhibitors' Godavari Biorefineries Ltd., Mumbai (Total Outlay Rs. 9,00,000) (January 1, 2023 - December 31, 2023).    JAN  2023      
4 Research Project Sanctioned Ongoing: ‘Phase 1 Clinical Development of Treatment Modalities for SARS-CoV-2 Infection and Related Complications’ sanctioned by DBT-BIRAC under COVID-Suraksha Scheme (Co-PI) (Total Outlay: Rs. 420.20 lakh)(July 2023-June 2024)    JULY  2023      
5 Research Project Sanctioned Completed: Industry-Sponsored Project: 'Studies involving Agrochemical Formulation' sponsored by Brizo Services, Navi Mumbai (April 25 to June 24, 2022)    APRIL  2022      
6 Research Project Sanctioned Ongoing: Crocetin Bio-production in Microalgae: A Novel Route to Oxygen-Diffusion Enhancing Phytochemicals and Its Semisynthetic Analogs sanctioned by SERB, DST (Co-PI)(Total Outlay: Rs. 29.59 lakh)(July 2022-March 2025)    JULY  2022      
7 Consultancy Project Handled Completed: 'Development of Deuterated Solvents, APIs and Impurities' Panopharm, Mumbai (April 1, 2022-March 31, 2023).    APRIL  2022      
8 Consultancy Project Handled Completed: 'Preclinical Development of a New Chemical Entity (NCE)' Godavari Biorefineries Ltd., Mumbai (January 2022 - December 2022)    JAN  2022      
9 Consultancy Project Handled Completed: 'Investigations of Capsule Excipients' - Research Project from ACG Associated Capsules Pvt. Ltd., Mumbai (Duration: 2 Months)    JAN  2022      
10 Research Project Sanctioned Ongoing: Industry-sponsored Project: 'Lead Optimization Studies of Phytochemicals, Their Analogs and Derivatives' sponsored by MinoniM Life Sciences Pvt. Ltd., Mumbai (January 20, 2022 to January 19, 2025)    JAN  2022      
11 Consultancy Project Handled Ongoing: Bioinspired Drug Discovery and Development; MinoniM Life Sciences Pvt. Ltd., Thane (April 1, 2021 to March 31, 2023)    APRIL  2021      
12 Consultancy Project Handled Completed: Preclinical Development of a New Chemical Entity (NCE); Godavari Biorefineries Ltd., Mumbai (January 2021 - December 2021)    JAN  2021      
13 Research Project Sanctioned Ongoing: ‘SWASHRAY (Self-Reliance in Working Around Sustainable, Helpful, Reliable and High-Yielding Processes and Technologies)’ – Department of Science and Technology (DST) under the scheme ‘Promotion of University Research and Scientific Excellence (PURSE)’ – 2020 (Total Outlay 26 Cr.) (PI) (March 2021 – March 2025)    APRIL  2021      
14 Consultancy Project Handled Completed: Preclinical Development of a New Chemical Entity (NCEs); Godavari Biorefineries Ltd., Mumbai (January 2020 - December 2020)    JAN  2020      
15 Consultancy Project Handled Completed: Advent ChemBio Pvt. Ltd., Navi Mumbai (January 2020 - June 2020)    JAN  2020      
16 Consultancy Project Handled Completed: Preclinical Development of a New Chemical Entity (NCE); Godavari Biorefineries Ltd., Mumbai (January 2019 - September 2019)    JAN  2019      
17 Consultancy Project Handled Completed: Design and Development of New Chemical Entities (NCEs); Godavari Biorefineries Ltd., Mumbai (January 2018 - December 2018).    JAN  2018      
18 Consultancy Project Handled Completed: Synthesis of few select API impurities; SpargeChem Pvt. Ltd., Pune (March 2018 - June 2018)    MAR  2018      
19 Research Project Sanctioned Completed: Evaluation of XARTM for Anti-Aging Effects (Epigeneres Pvt. Ltd., Mumbai)(January 2018-April 2018)    JAN  2018      
20 Research Project Sanctioned Completed: Evaluation of XARTM for the Treatment of Polycystic Ovarian Syndrome using a Mice as an Animal Model (Epigeneres Pvt. Ltd., Mumbai)(October 2017-December 2017)    OCT  2017      
21 Consultancy Project Handled Completed: Medicinal Chemistry of Novel Cancer Stem Cell (CSC) Inhibitors; Godavari Biorefineries Ltd., Mumbai (January 2017 - December 2017)    JAN  2017      
22 Consultancy Project Handled Completed: Scale-up of a Major Intermediate of a Lead Molecule; Godavari Biorefineries Ltd., Mumbai (April 2017 - June 2017)    APRIL  2017      
23 Consultancy Project Handled Completed: Systematic Structure-Activity Relationship (SAR) investigations of a Series of New Chemical Entities (NCEs); Godavari Biorefineries Ltd., Mumbai (January 2016 - December 2016)    JAN  2016      
24 Research Project Sanctioned Completed: Targeting Therapy-resistant Cancer Stem Cells (BIPP/BIRAC/DBT) (Sanctioned) (Collaborator) (Along with Godavari Biorefineries Ltd., Mumbai) (Total Outlay Rs. 1.5 Cr)    MAR  2016      
25 Research Project Sanctioned Completed: Development of Novel Fluorescent Substrates for Enzyme Sensitive Assays of Aminoacylases, Trypsin and Chymotrypsin (SVKM’s NMIMS)(November 4, 2016 - October 1, 2019) (PI)    NOV  2016      
26 Research Project Sanctioned Completed: Comparative Evaluation of Microcrystalline Cellulose obtained from Bagasse (MCC-B) with Pharmaceutical Grade MCC. Industry Project sponsored by Godavari Biorefineries Ltd., Mumbai. (February 1 – April 30, 2015) (PI)    FEB  2015      
27 Consultancy Project Handled Completed: Modifications of a Natural Lead; Godavari Biorefineries Ltd., Mumbai (January 2015 - December 2015)    JAN  2015      
28 Research Project Sanctioned Completed: Design and Development of Novel Inhibitors of Inosine 5’-Monophosphate Dehydrogenase II (IMPDH II) as Anti-inflammatory Agents (DST/SERB) (Sanction Order No. SERB/F/60/2014-15 dated 09.04.2014) (Total Outlay Rs. 25,75,903/-) (PI) (May 28, 2014-May 27, 2017)(PI)    MAY  2014      
29 Research Project Sanctioned Completed: Discovery of Inhibitors of System Xc¯ Transporter, a Novel Therapeutic Target for Glutamate-Mediated Excitoxicity and Epileptogenesis (DBT/NTF) (Reference No. BT/PR4605/MED/30/719/2012) (September 2012-August 31, 2015) (Co-PI) (Total Outlay Rs. 18.16 lakh)    SEPT  2012      

Paper Published
1 International Journal Khairnar S, Sonawane A, Cheke RS, Kharkar PS, Gaikwad V, Patil S, Aware V. Hit discovery of novel 2-phenyl-substituted 4-amino-6,7-dihydro-5H-cyclopenta[d]pyrimidines as potential anti-glioblastoma therapeutics: Design, synthesis, biological evaluation, and computational screening. Drug Dev Res. 2023;84(3):561-578. doi: 10.1002/ddr.22046. [Clarivate Analytics Impact Factor (2021): 5.004]    MAY  2023      
2 International Journal Peerzada Z, Shah MD, Kharkar PS, Desai KB. Exploration of the inhibitory effect of Cassia fistula on quorum sensing mediated virulence factor production and biofilm activity in Pseudomonas aeruginosa: an in vivo study in model organism Caenorhabditis elegans. J Med Microbiol. 2023;72(2). doi: 10.1099/jmm.0.001578. [Clarivate Analytics Impact Factor (2021): 3.196]    FEB  2023      
3 National Journal Thakur, V. P.; Bagwe, P. V.; Kharkar, P. S.; Joshi, S. V. Synthesis, structural characterization and solubility investigation of flurbiprofen isobutanol ammonium salt. Indian Drugs 2023, 60(11), 19-27. [Indexed in Scopus].    DEC  2023      
4 International Journal Cheke, R. S.; Kharkar, P. S. Covalent inhibitors: An ambitious approach for the discovery of newer oncotherapeutics. Drug Develop. Res. 2023 (In Press) [Clarivate Analytics Impact Factor (2022): 3.8].    DEC  2023      
5 International Journal Mishra, S.; Prabhakar, B.; Kharkar, P. S.; Pethe, A. M. Banana peel waste: An emerging cellulosic material to extract nanocrystalline cellulose. ACS Omega 2023, 8(1), 1140-1145. [Clarivate Analytics Impact Factor (2021): 4.132].    JAN  2023      
6 International Journal Bagwe, Pritam V.; Thakur, Vaibhavi P.; Kharkar, Prashant S.; Joshi, Shreerang V. Mycophenolic acid isobutanolammonium salt: synthesis, structural characterization, and solubility investigations. J. Therm. Anal. Calorim. 2023, 148, 4247-4254. [Clarivate Analytics Impact Factor (2021): 4.755].    MAR  2023      
7 International Journal Ponugoti, Sai S.; Vibuthe, Rutuja S.; Detke, Sandip J.; Kharkar, Prashant S.; Joshi, Shreerang V. Organocatalyzed ipso hydroxylation of aryl boronic acids in aqueous medium: A metal free approach. Syn. Comm. 2023, 53(12), 893906. [Clarivate Analytics Impact Factor (2021): 1.937]    APRIL  2023      
8 International Journal Bagwe, Pritam V.; Thakur, Vaibhavi P.; Kharkar, Prashant S.; Joshi, Shreerang V. Synthesis, characterization, and dissolution properties of Aceclofenac-isobutabolammonium salt. J. Ind. Chem. Soc. 2023, 100(11), 101093. [Clarivate Analytics Impact Factor (2022): 1.3].    NOV  2023      
9 International Journal Cheke, R. S.; Patel, H. M.; Patil, V. M.; Ansari, I. A.; Ambhore, J. P.; Shinde, S. D.; Kadri, A.; Snoussi, M.; Adnan, M.; Kharkar, P. S.; Pasupuleti, V. R.; Deshmukh, P. K. Molecular Insights into Coumarin Analogues as Antimicrobial Agents: Recent Developments in Drug Discovery. Antibiotics (Basel) 2022, 11(5), 566. [Clarivate Analytics Impact Factor (2021): 5.222].    MAY  2022      
10 National Journal Patil, Pritesh S.; Chakraborty, Aakash; Kadam, Shruti S.; Kharkar, Prashant S.; Patwardhan, Anand V.; Joshi, Shreerang V. Greener approach for process intensification of iron haematinics by membrane nanofiltration. J. Ind. Chem. Soc. 2022, 99, 100510. [Clarivate Analytics Impact Factor (2021): 0.243]    MAY  2022      
11 International Journal Ambhore, J. P.; Chaudhari, S. R.; Cheke, R. S.; Kharkar, P. S. A concise analytical profile of efavirenz: analytical methodologies. Crit. Rev. Anal. Chem. 2022, 52(7), 1583-1592 [Clarivate Analytics Impact Factor (2021): 5.686].    JULY  2022      
12 International Journal Bhowmik A, Chunhavacharatorn P, Bhargav S, Malhotra A, Akalya S, Kharkar PS, Nirmal NP, Chauhan A. Human Milk Oligosaccharides as Potential Antibiofilm Agents: A Review. 2022, 14(23), 5112 [Clarivate Analytics Impact Factor (2021): 6.706]    DEC  2022      
13 International Journal Telange, Darshan R.; Sohail, Nazish K; Hemke, Atul T.; Kharkar, Prashant S.; Pethe, Anil M. Phospholipid complex-loaded self-assembled phytosomal soft nanoparticles: Evidence of enhanced solubility, dissolution rate, ex vivo permeability, oral bioavailability, and antioxidant potential of mangiferin. Drug Deliv. Transl. Res. 2021, 11, 1056-1083. (DOI: 10.1007/s13346-020-00822-4) [Clarivate Analytics Impact Factor (2019): 2.664].    MAY  2021      
14 International Journal Joshi Shreerang V.; Joshi, Maithili; Danave, Ameya; Kharkar, Prashant S. Chemistry of iodinated contrast media: A Minireview. Mini-Rev. Org. Chem. 2021, 18(7), 885-901. [Clarivate Analytics Impact Factor (2020): 2.495].    JAN  2021      
15 International Journal Telange, Darshan R.; Jain, Shirish P.; Pethe, Anil M.; Kharkar, Prashant S.; Rarokar, Nilesh R. Use of combined nanocarrier system based on chitosan nanoparticles and phospholipids complex for improved delivery of ferulic acid. Int. J. Biol. Macromol. 2021, 171, 288-307. [Clarivate Analytics Impact Factor (2019): 5.162].    FEB  2021      
16 International Journal Shinde, Kailas W.; Kharkar, Prashant S.; Shah, Chetan P.; Rathod, Shrimant V. Synthesis, molecular docking and biological evaluation of novel 2-(3-chlorophenyl)quinoline-4-carboxamide derivatives as potent anti-breast cancer and antibacterial agents. Thai J. Pharm. Sci. 2021, 45(1), 41-49. [Indexed in Scopus].    JAN  2021      
17 International Journal Shah, Hriday; Jain, Ashvi S.; Joshi, Shreerang V.; Kharkar, Prashant S.* Crocetin and related oxygen diffusion-enhancing compounds: Review of chemical synthesis, pharmacology, clinical development and novel therapeutic applications. Drug Develop. Res. 2021, 82(7), 883-895. [Clarivate Analytics Impact Factor (2020): 4.360].    FEB  2021      
18 International Journal Sahoo, S.; Kharkar, Prashant S.; Sahu, Niteshkumar U.; Brijesh, S. Anxiolytic activity of Psidium guajava leaves ethanolic extract in mice subjected to chronic restraint stress. Phytotherapy Res. 2021, 35(3), 1399-1415. [Clarivate Analytics Impact Factor (2019): 4.087]. DOI: 10.1002/ptr.6900    MAR  2021      
19 National Journal Kharkar, Prashant S.; Shah, Chetan P.; Sahu, Niteshkumar U. Drug repurposing for Breast Cancer: Preliminary medicinal chemistry investigations and future perspectives. J. Indian Chem. Soc. 2020, 97, 1245-1250 [Clarivate Analytics Impact Factor (2019): 0.150].    AUG  2020      
20 International Journal Kharkar, Prashant S.* Cancer Stem Cell (CSC) inhibitors in oncology - A promise for a better therapeutic outcome: State of the art and future perspectives. J. Med. Chem. 2020, 63(24), 15279-15307. [Clarivate Analytics Impact Factor (2019): 6.205].    DEC  2020      
21 International Journal Kharkar, Prashant S. Computational approaches for the design of (mutant-)selective tyrosine kinase inhibitors: State-of-the-art and future prospects. Curr. Top. Med. Chem. 2020, 17, 1522-1533. (DOI: 10.2174/1568026620666200502005853) [Clarivate Analytics Impact Factor (2019): 3.218].    MAY  2020      
22 International Journal Padhariya, Komal; Athavale, Maithili; Srivastava Sangeeta; Kharkar, Prashant S.* Substituted chloroacetamides as potential cancer stem cell (CSC) inhibitors: Synthesis and biological evaluation. Drug Develop. Res. 2020, 81, 356-365. (DOI: 10.1002/ddr.21628) [Clarivate Analytics Impact Factor (2018): 1.902].    APRIL  2020      
23 International Journal Padhariya, Komal; Athavale, Maithili; Srivastava Sangeeta; Kharkar, Prashant S.* A novel series of substituted 1,2,3-triazoles as potential cancer stem cell (CSC) inhibitors: Synthesis and biological evaluation. Drug Develop. Res. 2020 (In Press) [Clarivate Analytics Impact Factor (2019): 1.902]    AUG  2020      
24 International Journal Kharkar, Prashant S.; Soni, Govind; Rathod, Vaibhavi; Shetty, Saritha; Gupta, M. K.; Yadav, Khushwant S. An outlook on procedures of conjugating folate to (co)polymers and drugs for effective cancer targeting. Drug Develop. Res. 2020, 81(7), 823-836.[Clarivate Analytics Impact Factor (2019): 1.902]    JUN  2020      
25 International Journal Sahoo, S.; Kharkar, Prashant S.; Sahu, Niteshkumar U.; Brijesh, S. Anxiolytic activity of Psidium guajava leaves ethanolic extract in mice subjected to chronic restraint stress. Phytotherapy Res. 2020. Published online on October 9, 2020. (DOI: 10.1002/ptr.6900) [Clarivate Analytics Impact Factor (2019): 4.087].    OCT  2020      
26 Book Chapter: Sahu, Niteshkumar U.; Shah, Chetan P.; Machhar, Janvhi S.; Kharkar, Prashant S. Drug Repurposing in Search of Anti-Infectives: Need of the Hour in the Multi-Drug Resistance Era! In: In Silico Drug Design; Roy, K., Ed.; 1st ed.; Academic Press, London: 2019; pp 399-426.    APRIL  2019      
27 International Journal Shah, Mayank, D.; Kharkar, Prashant S.; Sahu, Nitesh U.; Desai, Krutika, B. Potassium 2-methoxy-4-vinylphenolate: a novel hit exhibiting quorum-sensing inhibition in Pseudomonas aeruginosa via LasIR/RhlIR circuitry. RSC Adv. 2019, 9, 40228-40239. (DOI: 10.1039/C9RA06612H) [Clarivate Analytics Impact Factor (2018): 3.049].    DEC  2019      
28 International Journal Patel, Dhaval; Kharkar, Prashant S.; Gandhi, Neha S.; Kaur, Ekjot; Dutt Shilpi; Nandave, Mukesh. Novel analogs of sulfasalazine as system xc - antiporter inhibitors: Insights from the molecular modeling studies. Drug Dev Res. 2019, 80(6), 758-777. (DOI: 10.1002/ddr.21557) [Clarivate Analytics Impact Factor (2017): 2.646].    SEPT  2019      
29 International Journal Shah, Chetan P.; Purushothaman, Gayathri, Thiruvenkatam, Vijay; Kirubakaran, Sivapriya; Juvale, Kapil; Kharkar, Prashant S.* Design, synthesis and biological evaluation of Helicobacter pylori inosine 5'-monophosphate dehydrogenase (HpIMPDH) inhibitors. Further optimization of selectivity towards HpIMPDH over human IMPDH2. Bioorg. Chem. 2019, 87, 753-764. (DOI: 10.1016/j.bioorg.2019.04.001) [Clarivate Analytics Impact Factor (2017): 3.929].    JUN  2019      
30 International Journal Salunke, Nishant; Kharkar, Prashant S.; Pandita, Nancy. Study of degradation behavior of besifloxacin, characterization of its degradation products by LC-ESI-QTOF-MS and their in silico toxicity prediction. Biomed. Chromatogr. 2019, 33(6), e4489. (DOI: 10.1002/bmc.4489) [Clarivate Analytics Impact Factor (2017): 1.688].    JUN  2019      
31 International Journal Mishra, Shweta; Kharkar, Prashant S.; Pethe, Anil M. Biomass and waste materials as potential sources of nanocrystalline cellulose: Comparative review of preparation methods (2016 - Till date). Carbohydr. Polym. 2019, 207, 418-427. (DOI: 10.1016/j.carbpol.2018.12.004) [Clarivate Analytics Impact Factor (2017): 5.185].    MAR  2019      
32 International Journal Silbermann, Katja; Shah, Chetan P.; Sahu, Niteshkumar U.; Juvale, Kapil; Stefan, Sven M.; Kharkar, Prashant S.*; Wiese, Michael. Novel chalcone and flavone derivatives as selective and dual inhibitors of the transport proteins ABCB1 and ABCG2. Eur. J. Med. Chem. 2019, 164, 193-213. (DOI: 10.1016/j.ejmech.2018.12.019) [Clarivate Analytics Impact Factor (2017): 4.816].    FEB  2019      
33 International Journal Sahu, Niteshkumar U.; Purushothaman, Gayathri; Thiruvenkatam, Vijay; Kharkar, Prashant S.* Design, synthesis, and biological evaluation of Helicobacter pylori inosine 5'-monophosphate dehydrogenase (HpIMPDH) inhibitors. Drug Dev Res. 2019, 80(1), 125-132. (DOI: 10.1002/ddr.21467) [Clarivate Analytics Impact Factor (2017): 2.646].    FEB  2019      
34 International Journal Machhar, Janvhi S.; Mittal, Ansh; Agrawal, Surendra; Pethe, Anil M.; Kharkar, Prashant S.* Computational prediction of toxicity of small organic molecules: state-of-the-art. Physical Sciences Reviews 2019, 4(10). (DOI:10.1515/psr-2019-0009) [Clarivate Analytics Impact Factor (2017): 2.959].    OCT  2019      
35 International Journal Damani-Shah, Hetal; Saranath, Dhananjaya; Das, Soma; Kharkar, Prashant; Karande, Anjali. In-silico identification of small molecules targeting H-Ras and in-vitro cytotoxicity with caspase-mediated apoptosis in carcinoma cells. J. Cell. Biochem. 2019, 120(4), 5519-5530. (DOI: 10.1002/jcb.27836) [Clarivate Analytics Impact Factor (2017): 2.959].    APRIL  2019      
36 International Journal Shah, Chetan P.; Kharkar, Prashant S.* Discovery of novel human inosine 5'-monophosphate dehydrogenase 2 (hIMPDH2) inhibitors as potential anticancer agents. Eur. J. Med. Chem. 2018, 158, 286-301. (DOI: 10.1016/j.ejmech.2018.09.016) [Clarivate Analytics Impact Factor (2017): 4.816].    OCT  2018      
37 International Journal Shah, Chetan; Kharkar, Prashant S.* Newer human inosine 5'-monophosphate dehydrogenase 2 (hIMPDH2) inhibitors as potential anticancer agents. J. Enzyme Inhibit. Med. Chem. 2018, 33, 972-977. (DOI: 10.1080/14756366.2018.1474211) [Clarivate Analytics Impact Factor (2016): 4.293].    DEC  2018      
38 International Journal Sahu, Nitesh U.; Singh, V.; Ferraris, D. M.; Rizzi, M.; Kharkar, Prashant S.* Hit discovery of Mycobacterium tuberculosis inosine 5'-monophosphate dehydrogenase, GuaB2, inhibitors. Bioorg. Med. Chem. Lett. 2018, 28, 1714-1718. (DOI: 10.1016/j.bmcl.2018.04.045) [Clarivate Analytics Impact Factor (2016): 2.454].    JUN  2018      
39 International Journal Hoonjan, M.; Sachdeva, G.; Chandra, S.; Kharkar, Prashant S.; Sahu, N.; Bhatt, Purvi. Investigation of HSA as a biocompatible coating material for arsenic trioxide nanoparticles. Nanoscale 2018, 10, 8031-8041. (DOI: 10.1039/c7nr09503a) [Clarivate Analytics Impact Factor (2016): 7.367].    MAY  2018      
40 International Journal Warrier, Sona; Kharkar, Prashant S.* A coumarin based chemosensor for selective determination of Cu (II) ions based on fluorescence quenching. J. Lumin. 2018, 199, 407-415. (DOI: 10.1016/j.jlumin.2018.03.073) [Clarivate Analytics Impact Factor (2016): 2.686].    JULY  2018      
41 International Journal Tambe, Amruta; Pandita, Nancy; Kharkar Prashant S.; Sahu, Niteshkumar U. Encapsulation of boswellic acid with ß- and hydroxypropyl-ß-cyclodextrin: Synthesis, characterization, in vitro drug release and molecular modelling studies. J. Mol. Struct. 2018, 1154, 504-510. (DOI: 10.1016/j.molstruc.2017.10.061) [Thomson Reuters Impact Factor (2016): 1.753]    FEB  2018      
42 International Journal Warrier, Sona; Kharkar, Prashant S.* Highly selective on-off fluorescence recognition of Fe3+ based on a coumarin derivative and its application in live-cell imaging. Spectrochim. Acta A Mol. Biomol. Spectrosc. 2018, 188, 659-664. (DOI: 10.1016/j.saa.2017.07.068) [Thomson Reuters Impact Factor (2016): 2.536]    JAN  2018      
43 International Journal Acharya, Pratap; Bansal, Ranju; Kharkar, Prashant S. Hybrids of steroid and nitrogen mustard as antiproliferative agents: Synthesis, in vitro evaluation and in silico inverse screening. Arzneim. Forsch. 2018, 68, 100-103. (DOI: 10.1055/s-0043-118538) [Thomson Reuters Impact Factor (2016): 0.706].    FEB  2018      
44 International Journal Rhyman, L.; Tursun, M.; Abdallah, H. A.; Choong, Y. S.; Parlak, C.; Kharkar, P.; Ramasami, P. Theoretical investigation of the derivatives of favipiravir (T-705) as potential drugs for Ebola virus. Phys. Sci. Rev. 2018, 3(9), 20170198. (DOI: 10.1515/psr-2017-0198) [Indexed in Web of Science]    SEPT  2018      
45 International Journal Vaghela, Madhuri; Sahu, Niteshkumar; Kharkar, Prashant S.; Pandita, Nancy. In vivo pharmacokinetic interaction by ethanolic extract of Gymnema sylvestre with CYP2C9 (Tolbutamide), CYP3A4 (Amlodipine) and CYP1A2 (Phenacetin) in rats. Chem. Biol. Interact. 2017, 278, 141-151 (DOI: 10.1016/j.cbi.2017.10.015) [Thomson Reuters Impact Factor (2016): 3.143]    DEC  2017      
46 International Journal Dutta, Shreelekha; Kharkar, Prashant S.; Sahu, Niteshkumar U.; Khanna, Aparna. Molecular docking prediction and in vitro studies elucidate anti-cancer activity of phytoestrogens. Life Sci. 2017, 185, 73-84. (DOI: 10.1016/j.lfs.2017.07.015) [Thomson Reuters Impact Factor (2016): 2.936]    SEPT  2017      
47 International Journal Kharkar, Prashant S.* Cancer stem cell (CSC) inhibitors: a review of recent patents (2012-2015). Exp. Opin. Therap. Pat. 2017, 27(7), 753-761. (DOI: 10.1080/13543776.2017.1325465) [Thomson Reuters Impact Factor (2016): 3.012].    JULY  2017      
48 International Journal Kulkarni, Mahesh R.; Mane, Madhav S.; Ghosh, Usha; Sharma, Rajiv; Lad, Nitin, P.; Srivastava, Ankita; Kulkarni-Almeida, Asha; Kharkar, Prashant S.; Khedkar, Vijay, M.; Pandit, S. S. Discovery of tetrahydrocarbazoles as dual pERK and pRb inhibitors. Eur. J. Med. Chem. 2017, 134, 366-378. (DOI: 10.1016/j.ejmech.2017.02.062) [Thomson Reuters Impact Factor (2016): 4.519].    JULY  2017      
49 International Journal Murahari, M.; Kharkar, Prashant S.; Lonikar, N.; Mayur, Y. C. Design, synthesis, biological evaluation, molecular docking and QSAR studies of 2,4-dimethylacridones as anticancer agents. Eur. J. Med. Chem. 2017, 130, 154-170. (DOI: 10.1016/j.ejmech.2017.02.022) [Thomson Reuters Impact Factor (2016): 4.519].    APRIL  2017      
50 International Journal Gadekar, Pradip K.; Roychowdhury, Abhijit; Kharkar, Prashant S.; Khedkar, Vijay M.; Arkile, Manisha; Manek, Hardik; Sarkar, Dhiman; Sharma, Rajiv; Vijayakumar, V.; Sarveswari, S. Design, synthesis and biological evaluation of novel azaspiro analogs of linezolid as antibacterial and antitubercular agents. Eur. J. Med. Chem. 2016, 122, 475-487. (DOI: 10.1016/j.ejmech.2016.07.001) [Thomson Reuters Impact Factor (2015): 3.902].    OCT  2016      
51 International Journal Kharkar, Prashant S.*; Ramasami, Ponnadurai; Choong, Yee Siew; Rhyman, Lydia; Warrier, Sona. Discovery of anti-Ebola drugs: A computational drug repositioning case study. RSC Adv. 2016, 6, 26329–26340 (DOI: 10.1039/C6RA01704E) [Thomson Reuters Impact Factor (2014): 3.84].    MAR  2016      
52 National Journal Gala, Viraj C.; John, Nithya R.; Bhagwat, Ashok M.; Datar, Ajit G.; Kharkar, Prashant S.; Desai, Krutika B. Attenuation of quorum sensing-regulated behaviours by Tinospora cordifolia extract and identification of its active constituents. Ind. J. Med. Res. 2016, 144, 92-103. (DOI: 10.4103/0971-5916.193295) [Thomson Reuters Impact Factor (2015): 1.446]    JULY  2016      
53 International Journal Sahu, Niteshkumar U.; Kharkar Prashant S.* Computational drug repositioning: A lateral approach to traditional drug discovery? Curr. Top. Med. Chem. 2016, 16(19), 2069-2077. (DOI: 10.2174/1568026616666160216153249) [Thomson Reuters Impact Factor (2014): 3.402]    AUG  2016      
54 International Conference Book Chapter: Warrier, Sona; Kharkar, Prashant S. Inverse Virtual Screening in Drug Repositioning: Detailed Investigation and Case Studies. In: Proceedings of International Conference on Pure and Applied Chemistry (ICPAC)-2014, Mauritius, Ramasami, P., Ed., Springer 2016    OCT  2016      
55 International Conference Bhandare, Richie B.; Gao, R.; Canney, D. J.; Kharkar, Prashant S. Novel ?-Butyrolactone Derivatives as Muscarinic Receptor Antagonists: Pharmacophore Elucidation and Docking Analyses. In: Proceedings of International Conference on Pure and Applied Chemistry (ICPAC)-2014, Mauritius, Ramasami, P., Ed., Springer 2016    OCT  2016      
56 International Journal Chhabria, Sagar V.; Akbarsha, Mohammad A.; Li, Albert P.; Kharkar, Prashant S., Desai, Krutika B. In situ allicin generation using targeted alliinase delivery for inhibition of MIA PaCa-2 cells via epigenetic remodeling, oxidative stress and cyclin-dependent kinase inhibitor (CDKI) expression. Apoptosis 2015, 20(10), 1388-1409. (DOI: 10.1007/s10495-015-1159-4) [Thomson Reuters Impact Factor (2013): 3.614].    OCT  2015      
57 International Journal Shah, Chetan P.; Kharkar, Prashant S.* Inosine 5’-monophosphate dehydrogenase (IMPDH) inhibitors as antimicrobial agents: Recent progress and future perspectives. Fut. Med. Chem. 2015, 7(11), 1415-1429. (DOI: 10.4155/fmc.15.72) [Thomson Reuters Impact Factor (2013): 4.000].    NOV  2015      
58 International Journal Patel, Dhaval; Kharkar, Prashant S.; Nandave, Mukesh. Emerging roles of system Xc- antiporter and its inhibition in CNS disorders. Mol. Membr. Biol. 2015, 32(4), 89-116. (DOI: 10.3109/09687688.2015.1096972) [Thomson Reuters Impact Factor (2013): 1.729].    APRIL  2015      
59 International Journal Singasane, Namrata; Kharkar, Prashant S.; Ceruso, Mariangela; Supuran, Claudiu T.; Toraskar, Mrunmayee P. Inhibition of carbonic anhydrase isoforms I, II, IX and XII with Schiff's bases incorporating iminoureido moieties. J. Enz. Inhibit. Med. Chem. 2015, 30(6), 901-907. (DOI: 10.1021/ml500140t) [Thomson Reuters Impact Factor (2013): 2.383].    JUN  2015      
60 International Journal Kharkar, Prashant S.*; Borhade, Sheetal; Dangi, Arti; Warrier, Sona. In search of novel anti-inflammatory agents: Computational repositioning of approved drugs. J. Comput. Sci. 2015, 10, 215-224. (DOI: 10.1016/j.jocs.2015.01.002) [Thomson Reuters Impact Factor (2013): 1.512].    SEPT  2015      
61 International Journal Preeja, M. P.; Palivela, Hemant; Soman, K. P.; Kharkar, Prashant S. Ligand-based virtual screening using random walk kernel and empirical filters. Procedia Comput. Sci. 2015, 57, 418-427. (DOI: 10.1016/j.procs.2015.07.508) [Thomson Reuters Impact Factor (2012): None].    JUN  2015      
62 International Journal Warrier, Sona; Kharkar, Prashant S.* Fluorescent probes for biomedical applications- A patent review (2009-2014). Pharm. Patent Analyst 2014, 3(5), 543-560. (DOI: 10.4155/ppa.14.41) [Thomson Reuters Impact Factor (2012): None].    SEPT  2014      
63 International Journal Modi, Gyan; Sharma, Horrick; Kharkar, Prashant S.; Dutta, Aloke K. Understanding the structural requirements of hybrid (S)-6-((2-(4-phenylpiperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydro-naphthalen-1-ol and its analogs as D2/D3 receptor ligands: A three-dimensional quantitative structure-activity relationship (3D QSAR) investigation. Med. Chem. Comm. 2014, 5(9), 1384-1392. (DOI: 10.1039/C4MD00159A) [Thomson Reuters Impact Factor (2012): 2.722].    SEPT  2014      
64 International Journal Pichake, Jayashree.; Kharkar, Prashant S.; Ceruso, Mariangela; Supuran, Claudiu T.; Toraskar, Mrunmayee P. Carbonic anhydrase inhibitors: Design, synthesis and biological evaluation of novel sulfonyl semicarbazide derivatives. ACS Med. Chem. Lett. 2014, 5(7), 793-796. (DOI: 10.1021/ml500140t) [Thomson Reuters Impact Factor (2012): 3.311].    JULY  2014      
65 International Journal Kharkar, Prashant S.* Drugs acting on central nervous system (CNS) targets as leads for non-CNS targets. F1000Research 2014, 3, 40. (DOI: 10.12688/f1000research.3-40.v2) [Thomson Reuters Impact Factor (2012): None].    MAR  2014      
66 International Journal Kharkar, Prashant S.*; Warrier, Sona; Gaud, R. S. Reverse docking: A powerful tool for drug repositioning and drug rescue. Fut. Med. Chem. 2014, 6(3), 333-342. (DOI: 10.4155/fmc.13.207) [Thomson Reuters Impact Factor (2012): 3.310].    MAR  2014      
67 International Journal Dunkern, T.; Chavan, S.; Bankar, D.; Patil, A.; Kulkarni, P.; Kharkar, Prashant S.; Prabhu, A.; Goeble, H.; Rolser, E.; Burckhardt-Boer, W.; Arumugam, P.; Makhija, M. T. Design, synthesis and biological evaluation of novel inosine monophosphate dehydrogenase inhibitors. J. Enz. Inhib. Med. Chem. 2014, 29(3), 408-419. (DOI: 10.3109/14756366.2013.793184) [Thomson Reuters Impact Factor (2012): 1.495].    MAR  2014      
68 International Journal Ramdhave, Anup S.; Patel, Dhaval; Ramya, I.; Nandave, Mukesh; Kharkar, Prashant S. Targeting heat shock protein 90 for malaria. Mini Rev. Med. Chem. 2013, 13(13), 1903-1920. (DOI: 10.2174/13895575113136660094) [Thomson Reuters Impact Factor (2012): 2.865].    NOV  2013      
69 International Journal Agrawal, Madhavi; Kharkar, Prashant; Moghe, Sonali; Mahajan, Tushar; Deka, Vaishali; Thakkar, Chandani; Nair, Amruta; Mehta, Chirag; Bose, Julie; Kulkarni-Almeida, Asha; Bhedi, Dilip; Vishwakarma, Ram A. Discovery of thiazolyl-phthalazinone acetamides as potent glucose uptake activators via high-throughput screening. Bioorg. Med. Chem. Lett. 2013, 23(20), 5740-5743. (DOI: 10.1016/j.bmcl.2013.07.067) [Thomson Reuters Impact Factor (2011): 2.554].    OCT  2013      
70 International Journal Gopishetty, B. Zhang, S.; Kharkar, Prashant S.; Antonio, T.; Reith, M.; Dutta, Aloke K. Modification of agonist binding moiety in hybrid derivative 5/ 7-{[2-(4-Aryl-piperazin-1-yl)-ethyl]-propyl-amino}-5,6,7,8-tetrahydro-naphthalen-1-ol/ -2-amino versions: Impact on functional activity and selectivity for dopamine D2/D3 receptors. Bioorg. Med. Chem. 2013, 21, 3164-3174. (DOI: 10.1016/j.bmc.2013.03.059) [Thomson Reuters Impact Factor (2011): 2.921].    JUN  2013      
71 Book Chapter: Kharkar, Prashant S. In Silico Absorption, Distribution, Metabolism and Excretion. In: In Silico Drug Discovery and Delivery, Markus, L., Ed., Future Science Group, 2013, pp 149-162    AUG  2013      
72 International Journal Dunkern, T.; Prabhu, A.; Kharkar, Prashant S.; Goeble, H.; Rolser, E.; Burckhardt-Boer, W.; Arumugam, P.; Makhija, M. T. Virtual and experimental high-throughput screening (HTS) in search of novel inosine 5’-monophosphate dehydrogenase II (IMPDH II) inhibitors. J. Comput. Aided Mol. Des. 2012, 26, 1277-1292. (DOI: 10.1007/s10822-012-9615-5) [Thomson Reuters Impact Factor (2012): 3.84].    NOV  2012      
73 International Journal Ghosh, B.; Antonio, T.; Zhen, J.; Kharkar, P.; Reith, M. E.; Dutta, A. K. Development of (S)-N6-(2-(4-(isoquinolin-1-yl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo-[d]thiazole-2,6-diamine and its analogue as a D3 receptor preferring agonist: potent in vivo activity in Parkinson's disease animal models. J. Med. Chem. 2010, 53, 1023-1037. (DOI: 10.1021/jm901184n) [Thomson Reuters Impact Factor (2008): 4.898].    FEB  2010      
74 International Journal Kharkar, Prashant S.* Two-dimensional (2D) in silico models for absorption, distribution, metabolism, excretion and toxicity (ADME/T) in drug discovery. Curr. Top. Med. Chem. 2010, 10, 116-121. (Invited review) (DOI: 10.2174/156802610790232224) [Thomson Reuters Impact Factor (2008): 4.268].    JAN  2010      
75 International Journal Kharkar, Prashant, S.; Deodhar, Meenakshi N.; Kulkarni, Vithal M. Design, synthesis, anti-fungal activity, and ADME prediction of functional analogues of terbinafine. Med. Chem. Res. 2009, 18, 421-432. (DOI: 10.1007/s00044-008-9138-8) [Thomson Reuters Impact Factor (2008): 0.731].    JULY  2009      
76 International Journal Kharkar, Prashant S.; Batman, Angela M; Zhen, J.; Beardsley, Patrick M.; Reith, Maarten E. A.; Dutta, Aloke K. Synthesis and biological characterization of (3R,4R)-4-(2-(benzhydryl-oxy)ethyl)-1-((R)-2-hydroxy-2-phenylethyl)-piperidin-3-ol and its stereo-isomers for activity toward monoamine transporters. ChemMedChem 2009, 4, 1075-1085. (DOI: 10.1002/cmdc.200900085) [Thomson Reuters Impact Factor (2008): 3.15].    JULY  2009      
77 International Journal Kharkar, Prashant S.; Dutta, Aloke K. Metal –protein attenuating compounds (MPACs): An emerging approach for the treatment of neurodegenerative disorders. Curr. Bioactive Compounds 2008, 4, 57-67. (Invited review) (DOI: 10.2174/157340708785294226) [Thomson Reuters Impact Factor (2007): None].    APRIL  2008      
78 International Journal Kharkar, Prashant S.; Reith, Maarten E. A.; Dutta, Aloke K. Three-dimensional quantitative structure-activity relationship (3D QSAR) and pharmacophore elucidation of tetrahydropyran derivatives as serotonin and norepinephrine transporter inhibitors. J. Comput.-Aided Mol. Des., 2008, 22, 1-17. (DOI: 10.1007/s10822-007-9146-7) [Thomson Reuters Impact Factor (2016): 3.028].    JAN  2008      
79 International Journal Brown, Dennis A.; Kharkar, Prashant; Parrington, Ingrid; Reith, Maarten; Dutta, Aloke K. Structurally constrained hybrid derivatives containing octahydrobenzo[g or f]-quinolines moieties for dopamine D2 and D3 receptors: Binding characterization at D2/D3 receptors and elucidation of a pharmacophore model. J. Med. Chem. 2008, 51, 7806-7819. (DOI: 10.1021/jm8008629) [Thomson Reuters Impact Factor (2016): 6.259].    DEC  2008      
80 International Journal Schmitt, K. C.; Zhen, J.; Kharkar, P.; Mishra, M.; Chen, N.; Dutta, A. K.; Reith, M. E. A. Interaction of cocaine, benztropine-, and GBR12909-like compounds with wildtype and mutant human dopamine transporters: molecular features that differentially determine antagonist binding properties. J. Neurochem. 2008, 107, 928-940. (DOI: 10.1111/j.1471-4159.2008.05667.x) [Thomson Reuters Impact Factor (2016): 4.083].    NOV  2008      
81 Book Chapter: Kharkar, Prashant S., Reith, Maarten, E. A., Dutta, Aloke, K. Structure-Activity Relationship Study of Piperidine Derivatives for Dopamine Transporters In: Dopamine Transporters: Chemistry, Biology, and Pharmacology, Trudell, M., Izenwasser, S., Eds., Wiley, John & Sons, Incorporated 2008, pp. 233-264    JULY  2008      
82 International Journal Kharkar, Prashant S.; Kulkarni, V. M. A Proposed model of Mycobacterium avium complex dihydrofolate reductase and its utility for drug design. Org. Biomol.Chem. 2003, 1, 1315– 1322. (DOI: 10.1039/b212211a) [Thomson Reuters Impact Factor (2016): 3.564].    APRIL  2003      
83 National Journal Karki, R. G.; Gokhale, V. M.; Kharkar, P. S.; Kulkarni, V. M. Azole compounds designed by molecular modeling show antifungal activity as predicted. Ind. J. Chem. 2003, 42B, 372-381 [Thomson Reuters Impact Factor (2016): 0.353].    FEB  2003      
84 International Journal Kharkar, Prashant S.; Desai, B.; Varu, B.; Loriya, R.; Gaveria, H.; Naliapara, Y.; Shah, A.; Kulkarni, V. M. Three-dimensional quantitative structure-activity relationship of 1,4-dihydropyridines as antitubercular agents. J. Med. Chem. 2002, 45, 4858-4867. (DOI: 10.1021/jm020217z) [Thomson Reuters Impact Factor (2016): 6.259].    OCT  2002      
Achievements
1 Fellowship Elected as Fellow of Maharashtra Academy of Sciences (FMASc)    DEC  2022      
2 Fellowship Elected as Life Fellow, Indian Chemical Society    DEC  2021      
3 Registered Patent Agent Indian Patent Office    MAR  2019      
4 Best Researcher of the Year 2017-18 University-level award given during annual convocation for Best Research Output during the previous academic year    AUG  2018      
5 DST Foreign Travel Grant For presenting research work at Gordon Research Conference on Computer Aided Drug Design, West Dover, USA.    JULY  2017      
6 Best Poster Award International Conference on Pure and Applied Chemistry (ICPAC)-2016, Mauritius (Poster Presented by Dr. Chetan Shah)    JULY  2016      
7 Indian National Science Academy (INSA) Award Deputation to University of Mauritius, Mauritius, for one week under International Collaborating / Bilateral Exchange Programme of the Academy    DEC  2016      
8 Professional Certification SAS Certified Base Programmer for SAS 9    JUN  2016      
9 Professional Certification SAS Certified Predictive Modeler using SAS Enterprise Miner 13    SEPT  2016      
10 Professional Certification SAS Certified Visual Business Analyst: Exploration and Design using SAS Visual Analytics    JUN  2016      
11 Best Poster Award International Conference on Pure and Applied Chemistry (ICPAC)-2014, Mauritius (Poster Presented by Dr. Richie Bhandare)    JUN  2014      
12 DST Foreign Travel Grant For presenting research work at Gordon Research Conference on Bioorganic Chemistry, Andover, USA    JUN  2014      
13 Best e-Presentation Award Virtual Conference on Computational Chemistry (VCCC)-2014 organized by University of Mauritius, Mauritius    AUG  2014      
14 Best Poster Award International Conference on Pure and Applied Chemistry (ICPAC)-2014, Mauritius (Poster Presented by Dr. Sona Warrier)    JUN  2014      
15 All India Rank 1 (Percentile 99.96) Graduate Aptitude Test in Engineering (GATE)-1998 Examination    MAR  1998      

Patent
1 Anticancer Compounds    2021        
2 Compounds for the Inhibition of Unregulated Cell Growth    2019        
3 Use of Compounds for Treating Viral Infections    2020        
4 5-Hydroxy-1,4-Naphthalenedione for Use in the Treatment of Cancer    2020        
5 Pharmaceutical Composition and Process to Prepare the Same    2021        

Work Experience Information
From Date To Date Designation Organization Name
1 24/05/2011 30/06/2012 Senior Research Scientist Nycomed Pharma Pvt. Ltd., Mumbai
2 23/08/2018 18/10/2019 Professor SVKM's NMIMS, Mumbai
3 23/03/2009 20/05/2011 Research Scientist Piramal Life Sciences Pvt. Ltd., Mumbai
4 21/12/2020 31/08/2023 President, Institute Innovation Council (IIC) Institute of Chemical Technology (ICT), Mumbai
5 15/03/2004 31/01/2005 Junior Research Scientist Nicholas Piramal India Ltd., Mumbai
6 02/07/2012 22/08/2018 Associate Professor SVKM's NMIMS, Mumbai
7 01/12/2021 31/12/2024 Associate Dean, Academic Programmes Institute of Chemical Technology (ICT), Mumbai
8 01/11/2022 Co-ordinator ICT-NICE Venture Incubator and Foundation, Institute of Chemical Technology, Mumbai
9 01/10/2020 30/11/2021 Nodal Officer Institute of Chemical Technology (ICT), Mumbai
10 01/09/2003 13/03/2004 Lecturer - Pharmaceutical Chemistry Bharati Vidyapeeth's College of Pharmacy, Navi Mumbai
11 01/06/2023 Member, Board of Directors ICT-NICE Venture Incubator and Foundation (Section 8 Company)
12 01/03/2006 28/02/2009 Postdoctoral Fellow Wayne State University, Detroit, MI, USA
13 01/02/2005 25/02/2006 Executive - Cheminformatics Reliance Life Sciences Pvt. Ltd., Mumbai
Membership In Professional Societies
Description No Membership No Membership Information
1 UDCT Alumni Association (UAA) 6730PHM04L Life Member
2 Association of Pharmaceutical Teacher of India (APTI) MA/LM-2386 Life Member
3 Registered Patent Agent IN/PA-2986 Indian Patents Office
4 American Chemical Society 31468136 Regular Member
5 Indian Chemical Society 8470 (Life Fellow) Life Fellow of Indian Chemical Society
6 Maharashtra Academy of Sciences BLF1147 Fellow of Maharashtra Academy of Sciences (MASc)
7 INDIAN SOCIETY OF CHEMISTS AND BIOLOGISTS LF 1261/2023 Life Member
Training/Conferences/Short Term Courses Attended
Month Year Training attended Information
1 FEB 2019 One-Day International Symposium on Stem Cells & Cancer-India 2019, Mumbai, India
2 JAN 2018 National Conference on Chemistry of Materials & Biologicals, IIT Gandhinagar
3 DEC 2017 69th Indian Pharmaceutical Congress (IPC), Chitakara University, Rajapura, Punjab
4 JULY 2017 Gordon Research Conference (GRC) on Computer Aided Drug Design, West Dover, Vermont, USA
5 JULY 2016 The International Conference on Pure and Applied Chemistry (ICPAC 2016), Mauritius
6 AUG 2015 Virtual Conference on Computational Chemistry (VCCC)-2015, organized by University of Mauritius during August 1-31, 2015
7 FEB 2015 2nd International Congress of Society for Ethnopharmacology, organized by Department of Pharmaceutical Sciences, RTM Nagpur University and Society for Ethnopharmacology, India
8 JAN 2015 2nd International Conference on Frontiers in Biological Sciences, organized by NIT, Rourkela, Odisha, India
9 JUN 2014 The International Conference on Pure and Applied Chemistry (ICPAC 2014), Mauritius
10 SEPT 2013 Recent Advances in Computational Drug Design 2013 (RACDD-2013), IISc, Bangalore
11 JUN 2013 Gordon Research Conference (GRC) on Bioorganic Chemistry, Andover, New Hampshire, USA
12 FEB 2013 6th RBF International Symposium on Advances in Translational Research and Development, Ahmedabad, Gujarat, India
13 MAR 2013 19th ISCB International Conference (ISCBC-2013), Udaipur, Rajasthan, India
14 APRIL 2008 235th ACS National Meeting, New Orleans, LA, United States
15 JULY 2008 41st Mid-Atlantic Graduate Students Summit (MAGSS) held at Detroit, MI, USA
16 MAR 2007 233rd ACS National Meeting, Chicago, IL, United States
17 SEPT 2004 15th European Symposium on Structure-Activity Relationships (QSAR) and Molecular Modelling, Istanbul, Turkey
18 JUN 2006 39th Mid-Atlantic Graduate Students Summit (MAGSS) held at Columbus, OH, USA
19 SEPT 2005 Diversity Oriented Synthesis – 2005 at Waltham, Boston, MA, USA
20 FEB 2003 Bioactive Discovery in the New Millennium, Lorne, Victoria, Australia
21 JAN 2002 The International Symposium on Current Developments in Drug Discovery for Tuberculosis, Bangalore, India.
22 SEPT 2020 AICTE Training And Learning (ATAL) Academy Online FDP on "Computational Fluid Dynamics" from 2020-9-21 to 2020-9-25 at Symbiosis Institute of Technology, Pune
23 OCT 2020 AICTE Training And Learning (ATAL) Academy Online FDP on "Quantum Computing" from 2020-10-5 to 2020-10-9 at Vardhaman College of Engineering, Hyderabad, Telangana, India.
24 DEC 2020 Professional Development Training Programme for Faculty & Administrators of Project Institutions of Technical Education Quality Improvement Programme – III (TEQIP – III) (under the aegis of the National Project Implementation Unit, Ministry of Education, Government of India) conducted online from December 7-9, 2020, conducted by Indian Institute of Management (IIM), Visakhapatanam
25 DEC 2020 Short-Term Course under Technical Education Quality Improvement Programme-III (TEQIP-III) on 'Linear Algebra and Its Applications' conducted by Indian Institute of Technology Delhi (December 20-24, 2020)
Training/Conference/Short Term Courses Conducted
Month Year Training Conductted Information
1 NOV 2019 Delivered a lecture on 'Being Innovative versus Being Imaginative: Opportunities and Challenges for (To be) Pharmacists for Serving the Society' at AICTE-Sponsored Two-day National Conference on 'Need-Based Research and Development in Pharmaceutical Field for Serving Society', R. C. Patel Institution of Pharmaceutical Education and Research, Shirpur (November 24, 2019)
2 AUG 2019 Delivered a lecture on 'Computational Prediction of Toxicity End-points: State-of-the-Art and Future Perspectives' at AICTE-Sponsored Short-Term Training Programme on 'Medicinal Chemistry in Drug Discovery', School of Pharmacy and Technology Management, SVKM's NMIMS, Shirpur (August 27, 2019)
3 AUG 2019 Conducted a Hands-on Training on 'Free Resources for Computational Prediction of Physicochemical, Pharmacokinetic and Toxicity Properties' at AICTE-Sponsored Short-Term Training Programme on 'Medicinal Chemistry in Drug Discovery', School of Pharmacy and Technology Management, SVKM's NMIMS, Shirpur (August 27, 2019)
4 FEB 2018 Delivered a lecture on ‘Extending Consultancies’ at APTI (MS) Sponsored One-Day National Seminar on ‘Writing Manuscripts, Research Proposals and Extending Consultancies’, ADES’s Dadasaheb Balpande College of Pharmacy, Nagpur (February 24, 2018).
5 JAN 2018 Delivered a lecture on ‘Chemical Modification of Pharmaceutical Excipients and Their Applications’ at One-Week Faculty Development Program on ‘Excipients: An Uncharted Roadmap towards Healthcare Technology’, Shobhaben Pratapbhai Patel School of Pharmacy and Technology Management, SVKM’s NMIMS, Mumbai (January 5, 2018)
6 JUN 2019 Delivered a lecture on 'Preclinical Studies in Drug Discovery and Development: A Bird’s Eye View!' at AICTE-Sponsored Faculty Development Programme on 'Patent Oriented New Frontiers in Drug Design and Development, SKB College of Pharmacy, Kamptee (June 21, 2019)
7 DEC 2019 Delivered a lecture on 'Biostatistics: A Definitive Science' at One-day State-Level Seminar on 'Applications of Mathematical Principles in Pharmaceutical Research', C. U. Shah College of Pharmacy, SNDT Women's University, Mumbai (December 21, 2019)
8 JAN 2020 Delivered a talk on 'Computational Modeling of Drug Disposition' at One-Day Seminar on Computer-Aided Drug Delivery System', Bharati Vidyapeeth's College of Pharmacy, Navi Mumbai (Jnuary 25, 2020)
9 APRIL 2020 A Webinar Delivered on ‘Drug Repurposing in Today’s Challenging Times’: April 11, 2020; Organized by Biomall.in
10 APRIL 2020 A Webinar Delivered on the Topic ‘The Upside-Down World: The Changed Paragon of Education and Research’: April 15, 2020; Organized by Students from ICT, NIPER and other Higher Educational Institutions
11 MAR 2020 One-Day Workshop for Industry Personnel ‘ICH M7: Mutagenic Impurities in Pharmaceuticals’ in collaboration with MultiCASE, Inc. (USA) (March 5, 2020)
12 APRIL 2021 Delivered a lecture on 'Scientific Writing: How to create an impressive content?' at One-Week Online Short-Term Training Programme (STTP): Scientific Research Paper, Patents and Research Proposal Writing for Grants and an Ethics' sponsored by AICTE at R. C. Patel Institution of Pharmaceutical Education and Research, Shirpur (April 25-30, 2021)
13 NOV 2021 ATAL Academy Sponsored One-Week Online Faculty Development Programme (FDP) on 'Recent Advances in Sustainability, Innovation, Diversity and Education (SIDEs) in Pharmaceutical Sciences' - November 15-19, 2021
14 JAN 2022 Delivered a lecture on 'Challenges in the Discovery of Drugs for Viral Infections: Are we ready to deal?' at Online Faculty Development Programme on 'Emerging Trends in Pharmaceutical Research', School of Pharmacy, Vishwakarma University, Pune (January 6, 2022)
15 DEC 2021 Delivered a lecture on 'Basics of Research: How to Develop Scientific Temperament?' at Induction Programme for PG Students, Dr. D. Y. Patil Institute of Pharmaceutical Sciences and Research, Pune (December 30, 2021)
16 DEC 2021 Delivered a lecture on 'Intellectual Property Rights (IPRs) - Do we really know what we must know?' at IPR Lecture Series organized by Institution's Innovation Council, SMBT College of Pharmacy, Igatpuri (December 10, 2021)
17 APRIL 2022 Panelist in a Panel Discussion on the theme - Role of Chemical Sciences in achieving Sustainable Development Goals by 2030 in National Conference on the theme “Role of Chemistry in Achieving Sustainable Development Goals: Academia and Industry Perspectives" Organized by Department of Chemistry, K J Somaiya College of Science & Commerce, Mumbai in association with Chemistry Division, BARC (April 22-23, 2022)
18 DEC 2022 Delivered a lecture on 'Computer-Aided Molecular Design: State-of-the-Art and Applications in New-Age Drug Discovery' at 'A Hands-on Training Program on Computational Strategies for Design and Development of Pharmaceuticals" under the scheme of Synergistic Training Program Utilizing the Scientific and Technological Infrastructure (STUTI), an initiative by Department of Science and Technology, India, organized by Institute of Chemical Technology, Mumbai (PMU) and hosted by SVKM’s Dr. Bhanuben Nanavati College of Pharmacy, Mumbai (December 12-1, 2022)
19 JAN 2023 Delivered a lecture on 'Cancer Stemness Inhibitors as New-Age Therapeutics in the fight against Cancer: Promises, Challenges and Case Studies' at International Conference on Drug Discovery and Development: Reaching the Unreached (DDDRU-2023)', School of Pharmacy, S. R. T. M. University, Nanded, India (January 2-3, 2023)
20 OCT 2023 Delivered a lecture on 'Antibody-Drug Conjugates: Lethal Weaponry for Targeted Oncotherapeutics' at Department of Biotechnology (DBT)-sponsored Two-day International Conference on Advances in Biotechnology: Current Discoveries and Future Perspectives (ICAB-2023) hosted by Amity University, Mumbai (October 17-18, 2023)
21 JAN 2024 Delivered a lecture on 'Applications of Computational Techniques for Pharmaceutical Researchers: State-of-the-Art and Future Perspectives' (January 2, 2024) at Department of Technical Educations (DTE), Maharashtra State-Sponsored Faculty Development Programme on Computational Tools for Research, Government College of Pharmacy, Chhatrapati Sambhajinagar (Jan 2-6, 2024)
22 DEC 2023 Delivered a lecture on 'New Drug Approvals in India: Changing Paradigms in the Regulatory Framework' (December 1, 2023) at National-level Three-day Conference on Pharma Regulatory Affairs Conclave, 2023 (November 30 to December 2, 2023) at Bharati Vidyapeeth’s College of Pharmacy, C.B.D. Belapur, Navi Mumbai.

Certified Predictive Modeler dabbling in the ocean of Machine- and Deep Learning!

1. Subject Expert: Pharmaceutical Chemistry in Faculty of Science and Technology, Research and Recognition Committee, Savitribai Phule Pune University (January 2020 - December 2021)