Institute of Chemical Technology, Mumbai

Prof. G.U. Chaturbhuj

Professor

Department : Pharmaceutical Sciences and Technology

Date of Joining :29/04/2006

URL :

Email Address : gu.chaturbhuj[@]ictmumbai.edu.in

Phone [Mobile] 9082039081

Office Extention : 1111

Research Area : Catalysis, Organic Chemistry, API synthesis and process chemistry

Academic Information
Degree/Diploma Description year subject
1 Post Doc   Post Doctoral Research at Northeastern University, Boston. Massachusetts, USA 2013 Medicinal Chemistry Cannabinoid research
2 Ph.D.   Ph. D. (Tech.) 2012 Pharmaceutical Chemistry
3 M. Pharm   M. Pharm. Sc. 2000 Pharmaceutical Chemistry
4 B. Pharm   B. Pharm 1998 Pharmacy

Courses Taught : Pharmaceutical Analysis Theory and Laboratory for B Pharmacy, B Tech. (Pharma) and M Pharmacy First year.

Project Information
1 Research Project Sanctioned Design, synthesis and evaluation of cannabinoid receptor 2 selective agonist for treatment of neuropathic pain Amount: 16 Lakh    JUN  2013      
2 Research Project Sanctioned Synthesis of Library of 2-(Substituted Aryl)-3-(Substituted)thiophenes as Bioactive molecules Amount: 0.35 Lakh    JULY  2012      
3 Research Project Sanctioned Design, Synthesis and Biological Evaluation of 2-Phenyl-4,5-(substituted)thiophene 3-carboxylic acid derivatives as Anti-inflammatory agents Amount: 7.52 Lakh    JUN  2012      
4 Research Project Sanctioned Synthesis of Impurities of Agro Products Amount: 13.2 Lakh    NOV  2012      
5 Research Project Sanctioned Combinatorial Synthesis of Pharmacologically Significant Five Membered Heterocycles Amount: 0.4 Lakh    JULY  2007      

Paper Published
1 International Journal A new parallel, rapid, and green Knoevenagel condensation catalyzed by in-situ generated carbonic acid (CO2 (g) in water): Application to intermediate of AMG 837 Pawan Kudale, Kanchan Gavali, Dipak Pinjari, Ganesh Chaturbhuj : Journal - Results in Chemistry, Volume 5 , Pages 100833 , Publisher - Elsevier 2023    JAN  2023      
2 International Journal Sulfated Polyborate Catalyzed Improved Synthesis of Enamines and Enaminones Based Intermediates of Imatinib, Nilotinib and Ocinaplon ; Priyanka V Bandivadekar, Kanchan D Gavali, Ganesh U Chaturbhuj Journal - ChemistrySelect , Volume 8 , Issue 5 , Pages - e202204425 2023    FEB  2023      
3 International Journal Assay of iodine monochloride via iodination of 2-chloroaniline using reversed-phase liquid chromatography ; Chaturbhuj Ganesh Sutar Purushottam, Ajay Kumar : Journal - Separation Science Plus , Volume 5 , Publisher - Wiley Analytical Science 2023    MAR  2023      
4 International Journal Hydrazine: A Source of Pharmaceutically Bioactive Drugs \Pravin R. Bhansali Shubhangi S. Savale, Vijayendran K. K. Praneeth, Ganesh U. Chaturbhuj ; Book - A Review of Hydrazine and Its Applications , Pages 1-58 , Publisher - Nova Scientific Publisher 2023    MAR  2023      
5 International Journal Hydrazine Derivatives (Pyrazole, Pyridazine): A Source of Pharmaceutically Bioactive Drugs : Ganesh U. Chaturbhuj and Pravin R. Bhansali Shubhangi S. Savale, Neetu Talreja, Vijayendran K. K. Praneeth, Shashank M. Sonkusare ; A Review of Hydrazine and Its Applications , Pages 59-180 , Publisher - Nova Scientific Publisher 2023    MAR  2023      
6 International Journal Piperidinium borate catalyzed Knoevenagel condensation of carbonyl compounds with active methylenes : Kanchan D Gavali, Pawan R Kudale, Ganesh U Chaturbhuj : Journal - Tetrahedron Letters , Pages - 154537 , Publisher - Pergamon 5/2023    MAY  2023      
7 International Journal Vitamins as Nutraceuticals in Cancer ; Ganesh U. Chaturbhuj Tushar N. Lokhande, Komal S. Valve, Subhash S. Shinde, Khemchand R. Surana : Book - Preventive and Therapeutic Role of Nutraceutical Vitamin, Publisher - Apple Academic Press, USA 2023    SEPT  2023      
8 International Journal Phthaloylation of amines, hydrazines, and hydrazides by N-substituted phthalimides using recyclable sulfated polyborate: Prerna Ganwir, Swati Jaydeokar, Ganesh U Chaturbhuj, Journal - Results in Chemistry, Volume - 4, Pages-100293, Publisher-Elsevier jan-2022    JAN  2022      
9 International Journal A Comprehensive Biological and Synthetic Perspective on 2-Deoxy-d-Glucose (2-DG), A Sweet Molecule with Therapeutic and Diagnostic Potentials : Yasanandana S Wijayasinghe, Meenakshi P Bhansali, Maheshkumar R Borkar, Ganesh U Chaturbhuj, Brian S Muntean, Ronald E Viola, Pravin R Bhansali, Journal - Journal of Medicinal Chemistry , Volume - 65, Issue - 5,Pages 3706-3728, Publisher - American Chemical Society 2/2022    FEB  2022      
10 International Journal Aluminized Polyborate: A New and Eco-friendly Catalyst for the Synthesis of Symmetrical N,N’-Di(aryl/alkyl)formamidines : Priyanka Bandivadekar & Ganesh U. Chaturbhuj Anil S. Mali ;Journal of Organic Preparations and Procedures International, Publisher - Taylor & Francis Journals Publication date 3/2022    MAR  2022      
11 International Journal Catalyst-free, one-pot expeditious synthesis of polyhydroquinolines and 2-amino-4H-chromenes : Prerna Ganwir, Priyanka Bandivadekar, Pawan Kudale, Ganesh U Chaturbhuj ; Journal Research on Chemical Intermediates, Volume 48 Issue 8, Pages 3429-3447, Publisher - Springer Netherlands Publication date 8/2022    AUG  2022      
12 International Journal Wet copper-slag: A new and eco-friendly catalyst for Knoevenagel condensation : Prerna Ganwir, Ishwari Kale, Ganesh Chaturbhuj : Journal Sustainable Chemistry and Pharmacy , Volume 25, Pages - 100614, Publisher - Elsevier 4/2022    APRIL  2022      
13 International Journal N-(Phenylsulfonyl)Benzenesulfonamide: A New Organocatalyst for One-Pot, Solvent-Free Synthesis of Biginelli’s 3,4-Dihydropyrimidine-2(1H)-Thiones : Prerna Ganwir, Kanchan Gavali, Ganesh U Chaturbhuj : Journal Polycyclic Aromatic Compounds, Pages 1-10 , Publisher - Taylor & Francis 4/2022    APRIL  2022      
14 International Journal Sulfated polyborate catalyzed rapid and efficient electrophilic thiocyanation of activated arenes : Nilesh B Patil, Ganesh U Chaturbhuj , Journal - Tetrahedron Letters, Volume 96, Pages 153763, Publisher-Pergamon    APRIL  2022      
15 International Journal Aluminized Polyborate: A New and Eco-friendly Catalyst for One-pot Multicomponent Synthesis of 1,3-Diaryl-3-(arylamino)propan-1-ones via Mannich Reaction : Anil S Mali, Prerna Ganwir, Ganesh U Chaturbhuj , Journal Organic Preparations and Procedures International, Volume 54, Issue 4, Pages 338-345, Publisher - Taylor & Francis 7/2022    JULY  2022      
16 International Journal Sulfated Polyborate, a Novel Buffer for Low pH Mobile Phase on a Nonend Capped Stationary Phase in Reverse Phase Liquid Chromatography    JAN  2021      
17 International Journal One-Pot Expeditious Synthesis of 2-Amino-4, 6-(disubstituted) nicotinonitriles Using Activated Fuller’s Earth as Catalyst    AUG  2021      
18 International Journal Rapid, chemoselective and mild oxidation protocol for alcohols and ethers with recyclable N-chloro-N-(phenylsulfonyl)benzenesulfonamide    JUN  2021      
19 International Journal Sesamol and its derivative investigated as antiandrogen-A potential prevention to prostate cancer in rats;Abhishek Shah, Aarti Abhishek Shah, Deelip S Rekunge, Aravinda Pai, Ganesh U Chaturbhuj, K Nandakumar, Richard Lobo; bioRxiv 2021.04. 22.440973    APRIL  2021      
20 International Journal Sulfated polyborate-H2O assisted tunable activation of N-iodosuccinimide for expeditious mono and diiodination of arenes Balu Misal , Amey Palav , Prerna Ganwir , Ganesh Chaturbhuj ;Volume 74, 22 June 2021    JUN  2021      
21 International Journal Sulfated polyborate: A dual catalyst for the reductive amination of aldehydes and ketones by NaBH4 Prerna Ganwir, Ganesh Chaturbhuj;Volume 74, 22 June 2021, 153143    JUN  2021      
22 International Journal THE PROPHYLACTIC APPROACH OF SESAMOL AND 3',4 (METHYLENEDIOXY)ACETOPHENONE TO PREVENT ASSOCIATED CARDIOTOXICITY OF DOXORUBICIN AT HIGH DOSE IN PROSTATE CANCER RAT MODEL A. Shah, A. A. Shah, K. Nandakumar, D. S. Rekunge, G. U. Chaturbhuj, A. Kishore, P. G. Nayak and R. Lobo Rasayan Journal of Chemistry 1938-1946 2021/7/1    JULY  2021      
23 International Journal Solvent-free, Efficient Transamidation of Carboxamides with Amines Catalyzed by Recyclable Sulfated Polyborate Catalyst : Anil S Mali, Krishna Indalkar, Ganesh U Chaturbhuj; Journal- Organic Preparations and Procedures International Volume 53, Issue 4, Pages 369-378, Taylor & Francis- 2021/7/4    JULY  2021      
24 International Journal NCBSI/KI: A Reagent System for Iodination of Aromatics through In Situ Generation of I-Cl ;Amey Palav, Balu Misal, Ganesh Chaturbhuj; Journal-The Journal of Organic Chemistry Volume 86, Issue17, Pages 12467-12474, Publisher- American Chemical Society    AUG  2021      
25 International Journal A Revision of the Biginelli Reaction: A Combined Experimental and Pharmacological Investigation : Ganesh U Chaturbhuj and Tushar N Lokhande Shweta S Jadhav, Kavita T Daware, Kshitij S Varma, Khushbhu Patil, Shital J Patil Journal - DER PHARMA CHEMICA , Volume 13, Issue 10 ,Pages 15-24, 2021/12    DEC  2021      
26 International Journal Sulfated Polyborate Catalyzed Selective Friedlander Annulation for Synthesis of Highly Functionalized Quinolines Organic Preparations and Procedures International,52, 297-303    APRIL  2020      
27 International Journal Activator free, expeditious and eco-friendly chlorination of activated arenes by N-chloro-N-(phenylsulfonyl)benzene sulfonamide (NCBSI) Balu Misal Amey Palav Prerna Ganwir Ganesh Chaturbhuj Tetrahedron Letters, 63, 2021, 152689    JAN  2020      
28 National Journal In-vitro anti-cancer and in-vivo immunomodulatory activity of two new compounds isolated from wheatgrass (Triticum aestivum L.) Save, Swati ; Chander, Harish ; Patil, Mahendra ; Singh, Surjeet ; Satti, Naresh Kumar; Chaturbhuj, Ganesh ; Clement, Brian Indian Journal of Natural Products and Resources Vol 10, No 1, 9-22 (2019)    JAN  2019      
29 International Journal An efficient, green solvent-free protocol for the synthesis of 2,4,6-triarylpyridines using reusable heterogeneous activated Fuller’s earth catalyst Journal of the Iranian Chemical Society volume 15, pages2455–2462(2018) Rekunge, D. S., Kale, I. A., & Chaturbhuj, G. U.    JUN  2018      
30 International Journal Aluminized polyborate: a novel catalyst for the multicomponent solvent-free synthesis of alkyl 1,2,6-trisubstituted-4-[(hetero)arylamino]-1,2,5,6-tetrahydropyridine-3-carboxylates Journal of the Iranian Chemical Society volume 15, pages1399–1409(2018)    MAR  2018      
31 International Journal Three-component, solvent-free synthesis of Betti base catalyzed by sulfated polyborate Manisha S. Patil, Chetan K. Khatri & Ganesh U. Chaturbhuj Monatshefte für Chemie - Chemical Monthly volume 149, pages1453–1457(2018)    FEB  2018      
32 International Journal Activated Fuller’s earth: an efficient, inexpensive, environmentally benign, and reusable catalyst for rapid solvent-free synthesis of 1-(amido/amino)alkyl-2-naphthols Deelip S. Rekunge, Hersh S. Bendale & Ganesh U. Chaturbhuj Monatshefte für Chemie - Chemical Monthly volume 149, pages1991–1997(2018)    AUG  2018      
33 National Journal A Precise Review on Tenofovir Disoproxil Fumarate: An Analytical Profile Vinod A. Chaure, Saurabh B. Ganorkar, Ganesh U. Chaturbhuj, Sanjay J. Surana and Atul A. Shirkhedkar Journal of Pharmaceutical Technology, Research and Management, 6, 153-167 (2018)    JUN  2018      
34 International Journal Repurposing n-butyl stannoic acid as highly efficient catalyst for direct amidation of carboxylic acids with amines Santoshkumar M. Potadar Anil S. Mali Krishnakant T. Waghmode Ganesh U. Chaturbhuj Tetrahedron Letters, 59, 4582-4586    DEC  2018      
35 International Journal m-CPBA–NH3(g) System: A Safe and Scalable Alternative for the Manufacture of (Substituted) Pyridine and Quinoline N-Oxides† Amey Palav, Balu Misal, Anilkumar Ernolla, Vinod Parab, Prashant Waske, Dileep Khandekar, Vinay Chaudhary, and Ganesh Chaturbhuj Org. Process Res. Dev. 2019, 23, 2, 244–251    DEC  2018      
36 International Journal Computational Analysis of the Binding Site(s) of TNF ß-TNFR1 Complex: Implications for Designing Novel Anticancer Agents Khatal, Trupti K.; Chaturbhuj, Ganesh Ulhasrao Clinical Cancer Drugs, Volume 5, Number 2, 2018, pp. 94-104(11)    FEB  2018      
37 International Journal Triazole hybrids as new type of anti-fungal agents Arabian Journal of Chemistry, Volume 10, Issue 3, March 2017, Pages 295-299 Pankaj B. Miniyar Anand A. Mahajan Santosh N. Mokale Mauli U. Shah Ashish S. Kumar Ganesh U .Chaturbhuj    MAR  2017      
38 International Journal Sulfated polyborate catalyzed Kabachnik-Fields reaction: An efficient and eco-friendly protocol for synthesis of a-amino phosphonatesTetrahedron Letters, Volume 58, Issue 7, 15 February 2017, Pages 694-698 Chetan K. Khatri Vardhan B. Satalkar Ganesh U. Chaturbhuj    FEB  2017      
39 International Journal Sulfated polyborate: An efficient and reusable catalyst for one pot synthesis of Hantzsch 1,4-dihydropyridines derivatives using ammonium carbonate under solvent free conditions, Tetrahedron Letters Volume 58, Issue 12, 22 March 2017, Pages 1240-1244 Deelip S. Rekunge, Chetan K. Khatri, Ganesh U. Chaturbhuj,    MAR  2017      
40 International Journal Rapid, efficient and eco-friendly procedure for the synthesis of quinoxalines under solvent-free conditions using sulfated polyborate as a recyclable catalyst, Journal of Chemical Sciences, February 2017, Volume 129, Issue 2, pp 141–148. Krishna S Indalkar Chetan K Khatri, Ganesh U Chaturbhuj,    FEB  2017      
41 International Journal Sulfated polyborate: A mild, efficient catalyst for synthesis of N-tert-butyl/N-trityl protected amides via Ritter reaction, Journal of Chemical Sciences, April 2017, Volume 129, Issue 4, pp 415–420 Krishna S Indalkar, Chetan K Khatri, Ganesh U Chaturbhuj,    APRIL  2017      
42 International Journal Novel 2-phenyl-4,5,6,7-tetrahydro[b]benzothiophene analogues as selective COX-2 inhibitors: Design, synthesis, anti-inflammatory evaluation, and molecular docking studies, Volume 27, Issue 8, 15 April 2017, Pages 1721-1726 Chetan K. Khatri, Krishna S. Indalkar, Chandragouda R. Patil, Sameer N. Goyal, b Ganesh U.Chaturbhuj,    APRIL  2017      
43 International Journal Sulfated polyborate: mild, efficient and eco-friendly catalyst for the synthesis of 2,3-dihydroquinazolin-4(1H)-ones, Journal of the Iranian Chemical Society, August 2017, Volume 14, Issue 8, pp 1683–1689 Chetan K. Khatri, Manisha S. Patil, Ganesh U. Chaturbhuj,    AUG  2017      
44 International Journal Sulfated polyborate catalyzed Kindler reaction: a rapid, efficient, and green protocol, Monatshefte für Chemie - Chemical Monthly, August 2017, Volume 148, Issue 8, pp 1463–1468 Chetan K. Khatri, Anil S. Mali, Ganesh U. Chaturbhuj,    AUG  2017      
45 International Journal Expeditious and efficient synthesis of Strecker’s a-aminonitriles catalyzed by sulfated polyborate, Tetrahedron Letters, Volume 58, Issue 22, 31 May 2017, Pages 2144-2148 Krishna S. Indalkar, Chetan K. Khatri, Ganesh U. Chaturbhuj,    MAY  2017      
46 International Journal A reactant promoted solvent free synthesis of 3,4-dihydropyrimidin-2(1H)-thione analogues using ammonium thiocyanate, Tetrahedron Letters, Volume 58, Issue 18, 3 May 2017, Pages 1778-178 Chetan K.Khatri, Santoshkumar M. Potadar, Ganesh U. Chaturbhuj, 0    MAY  2017      
47 International Journal Rapid and efficient protocol for Willgerodt–Kindler’s thioacetamides catalyzed by sulfated polyborate, Monatshefte für Chemie - Chemical Monthly, December 2017, Volume 148, Issue 12, pp 2091–2095 Deelip S. Rekunge, Chetan K. Khatri, Ganesh U. Chaturbhuj,    DEC  2017      
48 International Journal Rapid, efficient and solvent-free synthesis of (un)symmetrical xanthenes catalyzed by recyclable sulfated polyborate, Tetrahedron Letters, Volume 58, Issue 29, 19 July 2017, Pages 2859-2864. Manisha S. Patil, Amey V. Palav, Chetan K. Khatri, Ganesh U. Chaturbhuj,    JULY  2017      
49 International Journal Sulfated polyborate catalyzed expeditious and efficient three-component synthesis of 3-methyl-4-(hetero)arylmethylene isoxazole-5(4H)-ones, Tetrahedron Letters, Volume 58, Issue 33, 16 August 2017, Pages 3256-3261. Manisha S. Patil, Chirag Mudaliar, Ganesh U. Chaturbhuj,    AUG  2017      
50 International Journal Sulfated polyborate-catalyzed efficient and expeditious synthesis of (un)symmetrical ureas and benzimidazolones, , Volume 58, Issue 45, 8 November 2017, Pages 4304-4307. Deelip S. Rekunge, Chetan K. Khatri, Ganesh U.Chaturbhuj,    NOV  2017      
51 International Journal Environmentally Benign, Highly Efficient and Expeditious Solvent-Free Synthesis of Trisubstituted Methanes Catalyzed by Sulfated Polyborate, Chemistry Select Volume 2, Issue 35, December 11, 2017, Pages 11693–11696 Valmik P. Jejurkar, Chetan K. Khatri, Dr. Ganesh U. Chaturbhuj, Dr. Satyajit Saha,    DEC  2017      
52 International Journal Sulfated polyborate catalyzed N-formylation of amines: A rapid, green and efficient protocol, Journal of the Iranian Chemical Society, December 2017, Volume 14, Issue 12, pp 2513–2519 Chetan K Khatri , G U Chaturbhuj,    DEC  2017      
53 International Journal Critical Molecular Determinants of a7 Nicotinic Acetylcholine Receptor Allosteric Activation, doi:10.1074/jbc.M115.692392 March 4, 2016 The Journal of Biological Chemistry291, 5049-50 Nicole A. Horenstein, Roger L. Papke, Abhijit R. Kulkarni, Ganesh U. Chaturbhuj, Clare Stokes, Khan Manther and Ganesh A. Thakur, 67    MAR  2016      
54 International Journal Sulfated polyborate: a new and eco-friendly catalyst for one-pot multi-component synthesis of 3,4-dihydropyrimidin-2(1H)-ones/thiones via Biginelli reaction, DOI: 10.1039/C6NJ03120J (Paper) New J. Chem., 2016, 40, 10412-10417 Chetan K. Khatri, Deelip S. Rekunge and Ganesh U. Chaturbhuj,    OCT  2016      
55 International Journal Activated Fuller’s earth as an inexpensive, eco-friendly, efficient catalyst for the synthesis of 5-aryl 1-H-tetrazole via [3+2] cycloaddition of nitriles and sodium azide, Tetrahedron Letters, Volume 57, Issue 51, 21 December 2016, Pages 5815-5819 Deelip S. Rekunge, Krishna S. Indalkar, Ganesh U. Chaturbhuj,    DEC  2016      
56 International Journal Copper catalyzed Gomberg-Buchmann–Hey reaction using aryldiazonium tosylate, Tetrahedron Letters, Volume 52, Issue 38, 21 September 2011, Pages 4950-4953 Ganesh U. Chaturbhuj, Krishnacharya G. Akamanchi,    SEPT  2011      
Achievements
1 Best Teacher Best Teacher elected by SY B Pharm students for teaching work for FY and SY Class    MAR  2019      
2 Post Doctoral Research Indo-US Raman Post-Doctoral fellowship for period of 1 year form UGC under Obama- Singh Knowledge Initiative 2012    OCT  2013      

Work Experience Information
From Date To Date Designation Organization Name
1 Sep. 2004 Sep 2005 Lecture in Pharmaceutical Analysis Sinhgad College of Pharmacy, Vadgaon, Pune
2 Sep 2015 Till date Associate Professor in Pharmaceutical Chemistry Institute of Chemical Technology, Mumbai
3 Oct. 2005 April 2006 Lecturer in Pharmaceutical Chemistry Sharadchandra College of Pharmacy, Otur, Dist.-Pune
4 Jan. 2002 Aug. 2004 Lecturer in Pharmaceutical Chemistry Seth Govind Raghunath Sable College of Pharmacy, Saswad, Pune
5 Aug. 2000 Dec. 2001 Research Associate RPG Life Sciences, Mumbai
6 April, 2006 August, 2007 Assistant Professor in Pharmaceutical Chemistry Institute of Chemical Technology, Mumbai
Membership In Professional Societies
Description No Membership No Membership Information
1 1. MA/LM-532 Life member The Association of Pharmaceutical Teacher of India (APTI)
2 2. Life member UDCT Alumni Association
3 3. Life Member Indian Society for Chemist and Biologist
Training/Conferences/Short Term Courses Attended
Month Year Training attended Information
1 OCT 2004 Orientation course entitled “ Analytical Instrumentation in Pharmaceutical Sciences- A practical Training Course” organized by B.V. Patel Pharmaceutical Education Research and Development Centre, Ahmedabad,
2 OCT 2007 Refresher course entitled “ Application of Analytical Techniques in Biological Sciences” organized by UGC Academic Staff College, University of Mumbai, at G.N. Khalasa College, Matunga, Mumbai
3 FEB 2008 Undergone AICTE-Quality Improvement Programme entitled “ Advances in Chromatographic Techniques” organized by Bharati Vidyapeeth University, Poona College of Pharmacy, Pune