Institute of Chemical Technology, Mumbai

Dr. SHIRISHKUMAR D AMBAVADE

Associate Professor

Department : Pharmaceutical Sciences and Technology

Date of Joining :10/08/2022

URL :

Email Address : sd.ambavade[@]ictmumbai.edu.in

Phone [Mobile] 9421640269

Office Extention : 2223

Research Area : Pharmacological evaluation of drugs acting on the central nervous system specifically, for memory enhancement, anti-Alzheimer's, antiepileptics, antidepressants, and antianxiety. Evaluation of the role of HDAC in CNS diseases and their pharmacotherapy. Development and evaluation of herbal-originated drugs for the treatment of CNS diseases and disorders, Gastrointestinal diseases, diabetes, and anti-inflammatory activity.

Courses Taught : Human anatomy and physiology, Pathophysiology, Pharmacology, Advance Pharmacology, Receptor Pharmacology, Molecular Pharmacology, Clinical Pharmacology, Research Methodology, Drug Regulatory Affairs, Pharmaceutical Jurisprudence

Paper Published
1 Muthal AP, Kulkarni R, Kumar D, Bagul C, Mukherjee-Kandhare AA, 1, Kandhare AD, Ambavade SD, Wagh V, Bodhankar SL. Cyclic adenosine monophosphate : Recent and future perspectives on various diseases. Journal of Applied Pharmaceutical Science 2022;12(03):1-15      2022      
2 Ambavade SD, Vanjari AV, Khot VS, Ghate BU. Trend and appraisal of research on Solanum xanthocarpum Schrad & Wendl: A Systematic Review. Current Trend in Pharmacy and Pharmaceutical Chemistry. 2021;3(2):1-55      2021      
3 SS Upadhye, S Balkundhi, VS Ghorpade, SD Ambavade, SV Abhang. Nanosponges: An Innovative Approach for Targeted Drug Delivery System. Research Journal of Pharmacy and Technology 2021;14(3):1797-1804.      2021      
4 Palshikar GS, Ambavade SD, Shanmugapandiyan P. A review on effect of seasonal variation on phytochemicals of medicinal plants. International Journal of Nutrition and Agriculture Research 2019;6(1):27-38      2019      
5 Lande AA, Ambavade SD*, Swami US, Adkar PP, Ambavade PD, Waghamare AB. Saponins isolated from roots of Chlorophytum borivilianum reduce acute and chronic inflammation and HDAC. Journal of Integrative Medicine 2015;13(1):25-33      2015      
6 Bang SR, Ambavade SD*, Jagdale PG, Adka PP, Waghmare AB, Ambavade PD. Lacosamide reduces HDAC levels in the brain and improves memory: Potential for treatment of Alzheimer's disease. Pharmacology, Biochemistry and Behavior 2015;134:65–69      2015      
7 Swami US, Lande AA, Ghadge PM, Adkar PP, Ambavade SD*. Pharmacological evaluation of Chlorophytum borivilianum Sant & Fern for anxiolytic activity and effect on brain GABA level. Oriental Pharmacy and Experimental Medicine 2014;14(2):169-180      2014      
8 Ambavade SD*, Misar AV. Ambavade PD. Pharmacological, nutritional, and analytical aspects of ß-sitosterol: a review. Oriental Pharmacy and Experimental Medicine 2014;14(3):193-211      2014      
9 Adkar PP*, Jadhav PP, Ambavade SD, Shelke TT, Bhaskar VH. Protective effect of leaf extract of Pandanus odoratissimus Linn on experimental model of epilepsy. International Journal of Nutrition, Pharmacology, Neurological Diseases 2014;4(2):81-87.      2014      
10 Ambavade SD,* Mitkari VC, Gaud IN, Adkar PP. Anxiolytic effect of ethanol extract of roots of Spilanthes acmella Murr in mice. International Journal of Advances in Pharmaceutical Research 2014;5(2):81-90      2014      
11 Jagdale PG, Ambavade SD*, Bang SR, Adkar PP, Salavi NC, Ambavade PD. Saponins from Rumex vesicarius reduces acute and chronic inflammation and HDAC. Journal of Pharmacy Research 2014;8(8):1074-1081      2014      
12 Adkar PP*, Ghadge PM, Ambavade SD, Shelke TT, Bhaskar VH. Effect of hydroethanol extract of leaves of Trapa bispinosa roxb on histological assessment in reproductive system of albino mice. Journal of Pharmacy Research 2014;8(4):570-575.      2014      
13 Adkar PP, Jadhav PP, Ambavade SD, Shelke TT, Bhaskar VH. Protective effect of leaf extract of Pandanus odoratismus linn on experimental model of epilepsy. International Journal of Nutrition, Pharmacology, Neurological Disease 2014;4(2):81-87      2014      
14 Adkar PP*, Jadhav PP, Ambavade SD, Bhaskar VH, Shelke T. Adaptogenic activity of lyophilized hydroethanol extract of Pandanus odoratissimus in swiss albino mice. International Scholarly Research Notices 2014;2014:1-10      2014      
15 Adkar PP, Dongare A, Ambavade SD, Bhaskar VH. Trapa bispinosa Roxb.: A Review on Nutritional and Pharmacological Aspects. Advances in Pharmacological Sciences 2014:2014:13      2014      
16 Adkar PP, Dongare A, Ambavade SD, Bhaskar VH. Effect of Trapa bispinosa on HDAC level in animal tissues for its anti-arthritic activity. Research journal of pharmaceutical, biological and chemical sciences. 2014, 5(4), pp. 1404–1415      2014      
17 Pathan D, Ambavade S. Investigation of anticonvulsant activity of Vanda roxburghii. Journal of Pharmacognosy and Phytochemistry 2014;2(6): 95-99.      2014      
18 Pathan D, Ambavade SD, “Anticonvulsant activity of ethanolic extract of Picrorhiza kurroa”, Pharmacophore 2014;5(1):141-146.      2014      
19 More SK, Lande AA, Jagdale PG, Adkar PP, Ambavade SD*. Evaluation of anti-inflammatory activity of Solanum xanthocarpum Schrad&Wendl (Kantakari) extract in laboratory animals. Ancient Science of Life. 2013;32(4):222-226      2013      
20 Bhagat R*, Misar AV, Ambavade SD, Kulkarni DK. HPTLC analysis and anti-inflammatory activity of Jatropha gossypifolia. L. root in mice and Wistar rats International Journal of Pharmacological Research 2013;3(1):13-18.      2013      
21 Adkar P, Shelake T, Ambavade S, Renke S, bhaskar V, Shoja MH. Effect of ethanol extract of Crataeva nurvala Buch-Ham on the some physiological parameters of reproduction in female rats. Global J Trad Med Sys 2012;1(1):16-20      2012      
22 Nesari T, Parchure SN, Mhetre NA, Ambavade SD, Bodhankar SL*. Study of shankhapushpi on spontaneous locomotor activity and anoxic stress in rodents. Pharmacologyonline 2011;2:253-262      2011      
23 Rani Bhagat, S. D. Ambavade, A. V. Misar and D. K. Kulkarni Anti-inflammatory activity of Jatropha gossypifolia L. leaves in mice and rats. Journal of Scientific and Industrial Research 2011;70:289-292      2011      
24 Ambavade SD, Mhetre NA, Muthal AP, Bodhankar SL*. Pharmacological evaluation of anticonvulsant activity of root extract of Saussurea lappa in mice. European Journal of Integrative Medicine 2009;1:131-137.      2009      
25 Ambavade SD, Mhetre NA, Muthal AP, Bodhankar SL*. Anxiolytic activity of root extracts of Decalepis hamiltonii W.A. in mice. Pharmacologyonline 2008;3:306-315      2008      
26 Mhetre NA, Ambavade SD, Muthal A, Bodhankar SL*, Thakurdesai PA. Beneficial effects of Benincasa hispida methanolic extract against neuroleptic disorders. Journal of Cell and Tissue Research 2006;6(2):775-778.      2006      
27 Ambavade SD, Mhetre NA, Tate VD, Bodhankar SL*. Pharmacological evaluation of extracts of Sphaeranthus indicus flowers on anxiolytic activity in mice. Indian Journal of Pharmacology 2006;38(4):254-259      2006      
28 Ambavade SD, Mhetre NA, Patil KM, Desai T, Bodhankar SL*. Anxiolytic activity of root extracts of Saussurea lappa Clark. in mice. Journal of Natural Remedies 2006;6/2:103-108      2006      
29 Mhetre NA, Ambavade SD, Bodhankar SL. Neuroleptic activity of water extract of D. hamiltonii W.A. (Shwet Sariva) roots. Indian Drugs 2006;43(3):231-234      2006      
30 Mhetre NA, Ambavade SD, Bodhankar SL*. Neuroleptic activity of extracts of Sphaeranthus indicus flowers in mice. Indian Journal of Natural Products 2006;22(2):24-27.      2006      
31 Ambavade SD, Mhetre NA, Baptista LM, Bodhankar SL*. Anticonvulsant activity of extracts of roots of Decalepis hamiltonii (Shwet Sariva) in mice. Deerghayu International 2003;03(75):232-236      2003